European UnionNon-profit, Private Business, Research Institution, Public Institution, Other

Interregional Innovation Investments Strand 2a

Interregional Innovation Investments Instrument Strand 2a

Funding Amount

Amount not specified

Deadline

13/11/2025

Eligible Organization Types

Non-profit, Private Business, Research Institution, Public Institution, Other

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What is the Interregional Innovation Investments Strand 2a Call?

Grant Description
This call supports interregional innovation investments by providing financial and advisory support to consortia of innovation actors across EU regions. It addresses digital, green and smart manufacturing priorities, aiming to demonstrate, scale up and commercialise mature innovations (TRL≥6) via an investment portfolio approach. Projects must foster cooperation between less developed, transition and more developed regions, create and integrate new value chains, and prepare robust exploitation p...
Required Results for Successful Funding

Expected Outcomes

Short-term (project closure):
• Creation of new value chains in less developed and transition regions.
• Deployment and adoption of innovative technologies and solutions (new to the region) by SMEs and public administrations.
• Demonstrable exploitation of research results through large-scale validation and market replication.
• Enhanced business confidence, competences and capacity to digitalise and grow.
• Contribution to digitisation and health system transformation.
• Uptake of reliable, viable solutions on the market.
• Deployment of green and digital technologies to strengthen EU manufacturing.
• Identification of funding sources and co-investment mechanisms.
• Strengthened innovation diffusion channels and interregional co-investment capacity.
Long-term:
• Reduced regional innovation divide and disparities between more and less developed regions.
• Increased productivity, efficiency and competitiveness of EU companies.
• Improved user-friendly, accessible and interoperable public services.
• Elevated digital skills and vocational training impact.
• New market opportunities and strengthened EU value chains.
• Support to the European Green Deal and twin green-digital transition.
• Positive environmental, health, security, climate and socio-economic impacts.
• Sustainable economic growth, job creation and reinforced European strategic autonomy.
Funded areas

Scope Requirements

To be eligible, proposals must:
• Address one thematic priority: Digital transition, Green transition or Smart manufacturing.
• Form consortia of innovation actors from the quadruple-helix ecosystem (industry, research, public authorities, civil society) in less developed, transition and more developed regions, with balanced participation.
• Operate under shared or complementary Smart Specialisation Strategies.
• Present an integrated interregional investment portfolio of several sub-projects that collectively address identified bottlenecks in a selected value chain.
• Demonstrate how each work package is interconnected across regions to achieve common objectives and ensure replicability.
• Start from mature investment ideas (TRL ≥ 6) and clearly describe the expected progression towards upscaling and commercialisation.
• Include an exploitation plan outlining post-project roll-out of new products, processes or services.
• Comply with ERDF regulation Article 13 and the 2025–2027 I³ Instrument Work Programme (Strand 2 a).
Additional Conditions for Applicants

Special Conditions

- Single-stage submission via Funding & Tenders Portal by 13 November 2025, 17:00 Brussels time.
• Admissibility: abide by page limits and layout rules (Section 5 of the call document and Part B of the Application Form).
• Eligibility: conform to country eligibility, financial and operational capacity, and exclusion criteria (Section 6 and 7).
• Financial set-up: governed by ERDF Regulation 2021/1058, EU Financial Regulation 2024/2509 and the Model Grant Agreement (MGA) I³.
• Cascade funding (FSTP): must follow the FSTP detailed budget and management rules.
• Evaluation: based on award criteria, scoring and thresholds (Section 9); indicative timeline per Section 4.
• Legal and administrative obligations: submission of S³ Compliance Declaration; use of approved templates; adhere to Funding & Tenders Portal Terms and Conditions.
Important dates

Open from: 22/05/2025

Deadline:13/11/2025

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