Tackling high-burden for patients and under-researched medical conditions
HORIZON-HLTH-2025-01-DISEASE-07
Funding Amount
Amount not specified
Deadline
16/09/2025
Eligible Organization Types
Non-profit, Private Business, Research Institution, Public Institution
Trusted by
What is the Tackling high-burden for patients and under-researched medical conditions Call?
Grant Description
This call supports multidisciplinary research into high-burden, under-researched medical conditions (such as chronic fatigue syndrome, autism, gynaecological diseases, low back pain and others) to improve understanding of pathophysiology, risk factors, diagnosis, monitoring, therapeutics and preventive strategies. It promotes robust scientific evidence, data sharing under FAIR principles, use of existing infrastructures, patient and caregiver engagement, social sciences and humanities integratio...
Required Results for Successful Funding
Expected Outcomes
- Scientific and clinical communities make effective use of state-of-the-art information, data, technologies, tools and best practices to better understand the targeted condition and support development of diagnostics, therapeutics and preventive strategies
• Enhanced exchange of data, knowledge and best practices within and beyond Europe, strengthening collaborations and building sustainable knowledge and care networks
• Wide use and further exploitation of newly established and relevant open access databases, integrated with existing FAIR-compliant infrastructures for storage and sharing of collected data
• Policymakers and funders are informed of research advances and consider ongoing support aligned with the sustainability of studies
• Constructive engagement of patients and caregivers in research, ensuring that research outcomes cater to their needs
• Health professionals have access to and adopt improved clinical guidelines on diagnosis and treatment of the condition
• Enhanced exchange of data, knowledge and best practices within and beyond Europe, strengthening collaborations and building sustainable knowledge and care networks
• Wide use and further exploitation of newly established and relevant open access databases, integrated with existing FAIR-compliant infrastructures for storage and sharing of collected data
• Policymakers and funders are informed of research advances and consider ongoing support aligned with the sustainability of studies
• Constructive engagement of patients and caregivers in research, ensuring that research outcomes cater to their needs
• Health professionals have access to and adopt improved clinical guidelines on diagnosis and treatment of the condition
Funded areas
Scope Requirements
- Target exactly one of the specified high-burden, under-researched medical conditions: myalgic encephalomyelitis/chronic fatigue syndrome; autism; gynaecological diseases; low back pain; or another high-burden under-researched condition (explicitly stated in the proposal)
• Exclude rare diseases (including rare cancers) and conditions already addressed under HORIZON-HLTH-2024-DISEASE-03-14-two-stage
• Demonstrate that the condition is insufficiently understood, inaccurately diagnosed or inadequately treated in a significant proportion of patients (supported by key literature)
• Address sex and gender-related aspects, age, ethnicity, socio-economic, lifestyle and behavioural determinants, as well as long-term emotional and societal effects on affected individuals
• Ensure multidisciplinary consortia with broad stakeholder representation (researchers, clinicians, SSH experts, patients/patient organizations, SMEs)
• Exploit and integrate FAIR-compliant open access data and databases, linking to existing infrastructures for storage and sharing
• Develop or refine policies and practices based on robust scientific evidence to improve diagnosis, treatment and patient care guidelines
• Exclude rare diseases (including rare cancers) and conditions already addressed under HORIZON-HLTH-2024-DISEASE-03-14-two-stage
• Demonstrate that the condition is insufficiently understood, inaccurately diagnosed or inadequately treated in a significant proportion of patients (supported by key literature)
• Address sex and gender-related aspects, age, ethnicity, socio-economic, lifestyle and behavioural determinants, as well as long-term emotional and societal effects on affected individuals
• Ensure multidisciplinary consortia with broad stakeholder representation (researchers, clinicians, SSH experts, patients/patient organizations, SMEs)
• Exploit and integrate FAIR-compliant open access data and databases, linking to existing infrastructures for storage and sharing
• Develop or refine policies and practices based on robust scientific evidence to improve diagnosis, treatment and patient care guidelines
Additional Conditions for Applicants
Special Conditions
- Proposals must explicitly state the single medical condition under study and focus solely on that condition
• Rare diseases (including rare cancers) and conditions covered by HORIZON-HLTH-2024-DISEASE-03-14-two-stage are out of scope
• Use of FAIR data principles is mandatory for all generated and shared datasets
• Inclusion of a clinical studies annex using the provided template is strongly encouraged
• Consortia must include social sciences and humanities expertise to address societal impact
• Startups and SMEs participation is strongly encouraged
• Balanced portfolio award: grants will be allocated not only by ranking but ensuring coverage across the different targeted medical conditions
• Evaluation thresholds: minimum score of 4 for each criterion (Excellence, Impact, Implementation) and cumulative minimum of 12
• Compliance with general admissibility, eligibility, financial and operational capacity conditions as per Horizon Europe General Annexes
• If using satellite-based earth observation or positioning data, beneficiaries must use Copernicus and/or Galileo/EGNOS services
• Entities assessed as high-risk suppliers of mobile network communication equipment are ineligible if topic is subject to network security restrictions
• Rare diseases (including rare cancers) and conditions covered by HORIZON-HLTH-2024-DISEASE-03-14-two-stage are out of scope
• Use of FAIR data principles is mandatory for all generated and shared datasets
• Inclusion of a clinical studies annex using the provided template is strongly encouraged
• Consortia must include social sciences and humanities expertise to address societal impact
• Startups and SMEs participation is strongly encouraged
• Balanced portfolio award: grants will be allocated not only by ranking but ensuring coverage across the different targeted medical conditions
• Evaluation thresholds: minimum score of 4 for each criterion (Excellence, Impact, Implementation) and cumulative minimum of 12
• Compliance with general admissibility, eligibility, financial and operational capacity conditions as per Horizon Europe General Annexes
• If using satellite-based earth observation or positioning data, beneficiaries must use Copernicus and/or Galileo/EGNOS services
• Entities assessed as high-risk suppliers of mobile network communication equipment are ineligible if topic is subject to network security restrictions
Important dates
Open from: 22/05/2025
Deadline:16/09/2025
Application period has ended
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